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A Phase III Comparison Of Prophylactic Cranial Irradiation (PCI) Versus Observation In Patients With Locally Advanced Non-Small Cell Lung Cancer

Primary Objective: Determine whether prophylactic cranial irradiation (PCI) improves survival after effective locoregional/systemic therapy for patients with locally advanced non-small cell lung cancer (LA-NSCLC). Secondary Objectives: Determine the neuropsychologic impact of PCI Determine the impact of PCI on QOL Determine the impact of PCI on the incidence of CNS metastases