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CyberKnife

Clinical Trials

Through the Parkview Research Center, cancer patients at Parkview have access to a number of clinical trials involving CyberKnife treatment. Patients interested in participating in one of the trials listed below should contact the CyberKnife coordinator at (260) 266-9165.

Eligibility to participate in a research study is determined by the patient’s oncologist, who will assess the patient’s condition based on criteria in the study’s protocols.

The following CyberKnife studies are available to patients:

Clinical trial for brain metastases

  • NCCTG 0574 – A Phase III international trial using CyberKnife Stereotactic Radiotherapy on patients with 1-3 brain metastases, with or without the addition of whole brain irradiation

Clinical trials for lung cancer

  • STARS – An international randomized study comparing the CyberKnife Stereotactic Radiotherapy with surgical resection in patients with stage I Non-Small Cell Lung Cancer
  • RTOG 0813 – Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) for Early-Stage, Centrally Located, Non-Small Cell Lung Cancer (NSCLC) in Medically Inoperable Patients
  • RTOG 1021 – A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High-Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)

Clinical trial for prostate cancer

  • CK Prostate II – An international study evaluating the use of CyberKnife Stereotactic Radiotherapy in patients with low- to intermediate-risk prostate cancer

Clinical trial for spine metastasis

  • RTOG 0631 – A phase II/III study of CyberKnife Stereotactic Radiotherapy in patients with localized spine metastasis
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